private label skincare

For global skincare brands, brightening products are still one of the most reliable categories for traffic, trial, and repeat purchase. Consumers may describe their needs in different ways: dark spots, post-acne marks, dullness, uneven tone, oily-looking skin, visible pores, or rough texture. Behind these different words is the same commercial question for brands: how can a brightening serum look effective enough to attract attention, but still feel comfortable enough for daily use?   This is why high-potency niacinamide serums continue to attract B2B interest. Public market references show that niacinamide is not only a mature ingredient, but also a growing product opportunity. Grand View Research reported the niacinamide beauty products market at USD 558.9 million in 2023 and USD 590.2 million in 2024, with a projected value of USD 846.5 million by 2030. As a dedicated skincare manufacturer, Aisen Pro Skin develops high-potency formulas that help brands capitalize on this growth with products designed for real market performance.   Niacinamide Beauty Products Market   However, growth does not mean every niacinamide serum will sell. The global market already has many 5%, 10%, 15%, and even higher-dose niacinamide products. For private label brands, importers, e-commerce sellers, spa channels, salons, and cosmetic manufacturers, the key is no longer simply adding niacinamide to a formula. The real challenge is building a product that can communicate stronger efficacy, better comfort, clearer positioning, and reliable OEM/ODM supply.   1. High Concentration Creates Attention, But It Also Creates Questions Concentration is one of the easiest product messages for consumers to understand. A 15% niacinamide serum immediately sounds stronger than an ordinary daily-use brightening serum. For online stores, marketplaces, social content, and importer catalogues, this gives the product a clear entry point. It can help customers quickly understand that the serum is designed for visible brightening, dark spot care, post-acne mark improvement, pore appearance, and smoother-looking skin.   But concentration also raises expectations. When a product says 15%, customers may ask whether it will feel sticky, whether it will cause flushing, whether it can be layered with other products, and whether it is suitable for repeated use. For B2B buyers, these questions matter because the first order is only the beginning. A serum that attracts trial but creates poor user experience may not generate stable reorders.   This is the point many brands overlook. High-potency brightening should not be presented as a simple race toward a higher number. A stronger commercial product needs a balance of concentration, purity, texture, comfort, product story, packaging, and supply support. Aisen Pro Skin develops High-Potency 15% Niacinamide Spot-Lightening Serum MELA B3 around this balance, helping global customers position the product as high-performance, but not harsh or difficult to use.     2. Low Nicotinic Acid Positioning Is a Professional Detail Brands Should Notice When developing a high-potency niacinamide serum, the quality of niacinamide matters. One professional point is the control of nicotinic acid-related impurities. In skincare discussions, nicotinic acid is often associated with flushing or temporary redness concerns. This does not mean every niacinamide product will cause discomfort, but it does explain why ingredient purity and formula design become more important when the concentration rises.   For a 15% niacinamide serum, brands should not only ask whether the formula contains niacinamide. They should also ask what kind of niacinamide is used, how the formula supports comfort, what skin feel the product has, and whether the product can be explained professionally in sales materials. These details help a brand move from a basic ingredient claim to a more credible high-performance brightening concept — exactly what many wholesale skincare suppliers look for when selecting trend-driven products for their catalogs.   Aisen MELA B3 uses 15% high-purity niacinamide with low nicotinic acid positioning. This gives B2B customers a more professional story for product pages, distributor materials, spa introductions, and private label sales kits. Instead of only saying high concentration, the product can be positioned around visible brightening, spot-lightening care, smoother-looking skin, refined-looking pores, and a more comfortable high-potency serum experience.     3. The Value of 15% Niacinamide Is Broader Than Brightening Alone Brightening is usually the first reason brands choose niacinamide, but it should not be the only product angle. A good 15% niacinamide serum can connect several consumer concerns into one product story. Many customers who search for dark spot serum may also care about post-acne marks. People who worry about dullness may also notice rough texture. Oily-skin consumers often look for products that can improve the look of pores without making the face feel heavy.   This is where niacinamide has strong commercial value. It can support a brightening line, an oily-skin care line, a post-acne mark care product, a pore-refining serum, or a smoother-texture routine. For e-commerce sellers, this means more search entry points. For importers and wholesalers, it means the product can be introduced to more retail channels. For spa and salon customers, it can work as a retail serum after professional care. For private label brands, it can become the hero SKU in a complete brightening series.   Aisen can help customers build this series logic instead of only selling one serum. MELA B3 may be paired with Vitamin C12 Serum 12% Pure Vitamin C Salicylic Acid for radiance and texture renewal, Aisen Salmon PDRN Facial Serum for repair-looking glow care, Korean Blue Copper Peptide Brightening Toner Serum Set for premium brightening routines, or centella ampoules, collagen masks, and repair creams for more complete skincare sets. This allows brands to build a stronger category plan while still keeping the 15% niacinamide serum as the main traffic product.     4. Skin Feel Decides Whether a Brightening Serum Can Move from Trial to Reorder A serum may win attention with its concentration, but it wins repeat purchase through skin feel. In many global markets, consumers prefer brightening serums that absorb quickly, layer well with sunscreen or makeup, and do not leave a heavy film. In humid markets, a lightweight fresh texture may be more attractive. In spa and salon channels, the product may need a more refined sensory feel. In e-commerce channels, before-and-after storytelling is important, but reviews will often mention texture, stickiness, fragrance, and comfort.   This is why B2B customers should evaluate more than the active ingredient list. Texture, pH range, fragrance direction, serum viscosity, absorption feel, packaging compatibility, and routine pairing all affect whether a formula can become a sellable product. A 15% niacinamide serum should feel advanced, but it should also be easy to understand and easy to use. For private label skin care products , these sensory details often decide whether a brand gets repeat orders or one-time sales.   Aisen supports texture adjustment, packaging selection, logo customization, label support, and product set development according to the customer's target market and sales channel. With 12 automated production lines, a 100,000-grade clean workshop, GMPC and ISO 22716 standards, 3,000+ mature skincare formulas, and annual capacity of up to 80 million units, Aisen can support both low-MOQ trial orders and scalable production. For customers testing a brightening serum category, this flexibility reduces development pressure. For mature brands, it supports long-term replenishment and category expansion.     5. Market Wording Should Be Clear, Flexible, and Product-Side Ready Brightening products face different claim expectations in different markets and sales channels. Some customers sell through cross-border e-commerce. Some work with importers and distributors. Some serve spa, salon, or professional retail channels. This does not mean every market needs the same wording, and it also does not mean a factory should promise one universal claim style for all countries.   For global B2B development, the safer approach is to prepare product-side materials clearly and leave final wording to be confirmed according to the target market, product category, sales channel, platform policy, and local requirements. Suitable cosmetic expressions may include helps improve the appearance of dark spots, visibly improves uneven-looking skin tone, helps reduce the look of post-acne marks, refines the appearance of pores, and supports a brighter, smoother-looking complexion.   Aisen can support customers with ingredient information, product specifications, COA, MSDS, carton information, packaging files, label materials, and export-related documents. These materials help customers communicate with importers, distributors, platform teams, or local consultants more efficiently, while keeping the factory's role focused on product development, production, quality control, documentation, and delivery.     6. Why Aisen MELA B3 Fits Global Private Label Brightening Projects Aisen High-Potency 15% Niacinamide Spot-Lightening Serum MELA B3 is designed for customers who want a stronger brightening serum without building a formula from zero. Its core value is a clear product position: 15% high-purity niacinamide, low nicotinic acid positioning, spot-lightening direction, post-acne mark care, pore-refining appearance, smoother-looking texture, and a fresh serum experience.   The product is also practical for B2B testing. With MOQ from 500 pieces and a typical lead time of 15-30 days, it can support startup brands, e-commerce sellers, importers, wholesalers, spa channels, salons, and product development companies that want to test a high-potency brightening SKU before scaling. As the product grows, Aisen can support packaging adjustment, logo customization, label support, bulk replenishment, export materials, and related skincare set development.   For customers who want a broader brightening or repair line, Aisen can recommend combinations around MELA B3. A brand may use MELA B3 as the main spot-lightening serum, Vitamin C12 Serum for radiance and exfoliation-inspired renewal, PDRN Facial Serum for repair-looking glow, Korean Blue Copper Peptide Brightening Toner Serum Set for premium daily care, and repair creams or masks for routine completion. This makes the niacinamide serum more than a single product. It becomes the anchor of a sellable skincare system. For skin care suppliers serving multiple channels, this portfolio approach makes it easier to present a complete brightening solution to downstream buyers.     Conclusion: A Strong Niacinamide Serum Needs More Than a Strong Number The future opportunity of 15% niacinamide is not only the concentration itself. The real commercial value comes from a complete product logic: visible brightening, comfort-oriented formula design, low nicotinic acid positioning, clear product wording, flexible packaging, stable supply, and export-ready support.   For global skincare brands, importers, e-commerce sellers, spas, salons, and private label customers, Aisen MELA B3 offers a mature starting point for developing a high-potency brightening serum. Share your target market, sales channel, packaging needs, expected order quantity, and brand positioning with Aisen. Our team can recommend a suitable 15% niacinamide serum solution or a complete brightening skincare set to help your brand turn market demand into a real product.   Sources Grand View Research. Niacinamide Beauty Products Market Size, Share & Trends Analysis Report. Related Products China Korean Blue Copper Peptide Brightening Toner Serum Set Supplier | aisenproskin.com China Vitamin C12 Serum 12% Pure Vitamin C Salicylic Acid Supplier | aisenproskin.com

  In the field of functional skincare, choosing a contract manufacturer essentially means selecting one based on the depth of its R&D, its quality control standards and its ability to collaborate. Guangzhou Aisen Biotechnology Co., Ltd. (Aisen), situated in Guangzhou’s Baiyun district—the heart of China’s beauty industry—does not define itself merely as a ‘contract manufacturer’. Instead, it uses scientific research as its foundation and a transparent supply chain as its commitment, empowering global brands to achieve sustained growth from inception to scale. Below, we explore four key dimensions to help you understand how Aisen has become the trusted technological engine behind these brands.   1.Led by nine PhDs, building a ‘superbrain’ for formulation research and development Aisen's core asset is a research and development team comprising nine professional PhDs and senior formulators, covering the entire chain from raw material research and development to formulation development and testing and certification. This "superbrain" has not only accumulated over 3,000 proven, effective formulations (covering the full range of categories including brightening, anti-ageing, repair, acne treatment and sun protection)—many of which have already been commercialised into market-validated products such as our Copper Peptide Repair Serum and Microencapsulated Retinol Renewal Serum—but also ensures that every product is "got right first time" from the laboratory to mass production. Furthermore, Aisen has established internship bases in collaboration with Jinan University and Guangzhou University, and has set up joint research institutes with Beijing Technology and Business University and South China Normal University, driving the "instant" translation of academic research into product efficacy. Industry-academia-research collaboration is not merely a slogan, but is embodied in the 3,000-plus validated solutions within Aisen's formulation library.     2.Patented technology combined with world-class ingredients sets new standards for efficacy Aisen adheres to a global sourcing strategy—working exclusively with leading suppliers (such as BASF, DSM and Hoda) to ensure that every batch of raw materials is traceable and its efficacy verifiable. From molecular encapsulation to raw material quality control, Aisen has resolved the apparent contradiction between "high efficacy" and "gentleness". Our Bakuchiol + Peptide Firming Serum, for instance, delivers retinol-like firming without irritation, while the PDRN Salmon DNA Ampoule accelerates barrier repair with zero downtime—both demonstrating this balance in practice.     3.Pharmaceutical-grade quality control system: delivering on our ‘transparency pledge’ through data Aisen adheres to the principle of a "transparent supply chain": its production facilities comply with GMPC standards and implement comprehensive quality control throughout the entire process, from raw material intake and emulsification/filling to the release of finished products. Every batch of products must pass stability testing (including a 6-month accelerated test at 40°C and freeze-thaw cycles at -10°C), preservative challenge tests and human patch safety tests, with traceable test reports issued for each batch. Quality control is not merely a slogan, but a set of verifiable data that Aisen delivers to every client. It is for this very reason that Aisen's products are exported to numerous markets across Europe, the Americas and Southeast Asia, and have helped many brands successfully pass local regulatory compliance reviews. Products ranging from our 12% Vitamin C + Salicylic Acid Serum to the Turmeric & Kojic Acid Cleansing Set have been routinely shipped to the US, Germany, and the Middle East with full CPNP/FDA/Halal documentation.     4.End-to-End Services: A one-stop service supporting brand growth from concept to market launch Aisen offers more than just contract manufacturing; we provide end-to-end support from concept to launch: 1. Strategic positioning – Based on market insights and efficacy trends, we assist brands in defining differentiated products; 2. Customised R&D – We incubate exclusive products from a library of over 3,000 formulations, rapidly developing formulations with high barriers to entry; 3. Eye-catching Design — We support the optimisation of standard packaging and the development of bespoke moulds, ensuring products have built-in viral appeal; 4. Flexible Production — Daily production capacity reaches 100,000 tubes of cream and 200,000 sheets of face masks (including customisable formats such as our Goat Milk & Silk Protein Soap Bar and Nourishing Skin Body Lotion), whilst supporting small-batch rapid response to reduce brand inventory pressure; 5. Global Compliance — We assist with the completion of MSDS, CPNP, FDA and other registrations, helping products reach the market swiftly.     Whether you are a start-up or an established business, Aisen can serve as your trusted long-term partner, offering flexible order sizes and professional technical support. Aisen’s philosophy is simple: to ensure every penny of your budget is spent on active ingredients, and to enable every brand to access R&D and quality control on a par with international luxury brands at an affordable cost. If you are seeking a skincare contract manufacturer that understands technology, values transparency and is committed to supporting you every step of the way, Aisen looks forward to discussing your needs with you.    

Meta Description: A practical guide for overseas skincare brands, importers, e-commerce sellers, salons, and cosmetic manufacturers looking for a reliable OEM/ODM partner with R&D, export support, quality control, Halal, Vegan, Clean Beauty options, and scalable production. Aisen skincare OEM/ODM factory production line for global private label brands. Many people face the same problems when choosing a skincare OEM/ODM factory. You contact several suppliers, and almost every one of them says the same things:they have  good quality, competitive price and fast delivery. Then you receive samples, but it is hard to know which formula is truly stable and which one only looks good at the sample stage. You want to develop a product for the United States, Europe, the Middle East, Southeast Asia, or another overseas market, but many factories simply send existing formulas instead of helping you understand your target market, compliance needs, ingredient trends, and consumer preferences.   Then more questions appear. Will the formula remain stable during shipping and storage? Will the packaging match the bulk product? What documents are required for export and import? Can the product support Halal, Vegan, Clean Beauty, or sensitive-skin-friendly positioning? If the first order sells well, can the factory support repeat orders and larger production?   For overseas brands, e-commerce sellers, importers, distributors, spa and salon businesses, and even foreign cosmetic manufacturers looking for a Chinese supply chain partner, choosing an OEM/ODM factory is not just about finding someone who can produce. It is about finding a partner who can help you develop, document, export, and supply products reliably.   Aisen  is built for this type of international cooperation. As a skincare OEM/ODM/OBM partner, Aisen supports global clients from product concept, market direction, formula development, packaging customization, sample testing, quality control, export documents, and global delivery to final market launch.   So, what should overseas customers pay attention to when choosing an OEM/ODM or OBM skincare manufacturer? Below are the key factors that can help you identify a reliable long-term partner.     1. Choose a Factory That Understands Your Target Market A reliable OEM/ODM factory should not only send a product list or quotation. It should understand your sales market firstly, target customers, channel, price range, and brand positioning  firstly.   Different markets have different expectations. For example, the US market often values clear efficacy claims, ingredient transparency, and strong brand storytelling. Europe pays close attention to compliance, mild formulas, sustainability, and Clean Beauty. The Middle East may require Halal-friendly products, fragranced body care, brightening care, and premium packaging. Southeast Asia often prefers lightweight textures, oil control, brightening, sun care, and skin barrier repair. A moisturizing brightening facial ampoule, for instance, can be tailored with different active ingredients, textures, and packaging styles to align with the unique demands of each target market.   When Aisen develops products for overseas clients, we start from the target market instead of simply copying existing formulas. We can support Halal-friendly, Vegan-friendly, Clean Beauty, sensitive-skin-friendly, plant-extract-based, alcohol-free, fragrance-free, or low-allergen product directions according to each project.     2. Make Sure It Can Support Export Documents and Compliance Many overseas customers think that once the formula and packaging are finished, the goods can simply be shipped and sold. In real international trade, documents, labels, ingredients, and import requirements are just as important as production.   Depending on the target market, customers may need COA, MSDS, ingredient lists, product specifications, label support, CPNP-related materials, FDA-related documentation, Halal documents, customs clearance files, and other export or compliance documents.   Aisen has long served global customers and understands the export process for skincare projects. We provide custom tailored facial skincare solutions for different market needs and support customers with FDA, CPNP, Halal, product information, label details, ingredient descriptions, and export-related documents based on project requirements. This helps brands, importers, e-commerce sellers, and foreign manufacturers launch compliant skincare products and enter local markets more smoothly.     3. Look for Halal, Vegan, and Clean Beauty Development Capability Overseas consumers increasingly care about the values behind a product. In addition to performance, they pay attention to lifestyle, religion, sustainability, safety, and transparency.   Halal skincare has stable demand in the Middle East, Southeast Asia, and Muslim consumer groups in Europe and North America. Clean Beauty, cruelty-free, alcohol-free, paraben-free, sulfate-free, and silicone-free concepts often appear on packaging, product pages, and advertising materials.   Aisen can help customers develop Halal-friendly, Vegan-friendly, Clean Beauty, sensitive-skin-friendly, plant-based, alcohol-free, fragrance-free, or low-allergen fragrance formulas. We can also support trend-driven ideas such as PDRN serum, peptide repair sets, niacinamide brightening products, retinol cream, brightening oil for dull skin, body oils, and baby skincare.     4. Check Whether It Has Real R&D Capability Many customers contact a factory with only a trend idea, a reference product, a packaging image, or a budget range. This is where R&D capability becomes critical.   A professional factory should translate your idea into a clear product plan, including efficacy direction, hero ingredients, formula structure, texture, fragrance, packaging format, cost range, MOQ, and production timeline.   Aisen has skincare R&D and production experience across anti-aging, brightening, acne care, repairing, moisturizing, sun care, body care, hair care, and baby skincare. Our R&D team can recommend mature formulas or support customized formula development when customers need a more differentiated product.     5. Evaluate Quality Control, Testing, and Production Capacity A good sample does not  mean stable bulk production. Once a project enters mass production, customers care about batch consistency, reliable delivery, and long-term supply.   A reliable factory should inspect raw materials, semi-finished products, packaging materials, production processes, and finished products. Testing may include microbiology, heavy metals, physicochemical indicators, appearance, odor, skin feel, stability, and packaging compatibility.   Aisen operates under GMPC and ISO 22716 standards, with modern production workshops, a 100,000-grade clean environment, 12 automated production lines, and annual capacity of up to 80 million units. We support low-MOQ trial orders and fast sampling, while also providing scalable production when a product succeeds. Aisen also maintains retained samples for raw materials, semi-finished products, and finished products to support batch traceability and risk control.     6. Choose a Partner That Supports Packaging and Brand Customization For overseas beauty brands, packaging is not only a container. It is part of the product’s selling power. On Amazon, Shopify, TikTok Shop, Instagram, retail shelves, salons, and spa channels, consumers judge quickly whether a product looks professional and trustworthy.   Different products need different packaging logic. Retinol, vitamin C, PDRN, and peptide serums may need light-protective, airless, or ampoule packaging. Body care products may work better in pump bottles, tubes, or gift sets. Masks need attention to pouch sealing and essence capacity. Baby skincare needs a gentle and safe visual message.   Aisen can support packaging selection, package design, logo customization, label support, set development, and product visual direction, helping customers build a finished product that can be presented, shipped, listed, promoted, and sold.     Conclusion When choosing an OEM/ODM factory, overseas customers should not look only at price, samples, and MOQ. The more important question is whether the factory can understand your target market, support export documents, develop market-friendly formulas, maintain quality systems, scale production, and help you build a product that is ready for international sales.   Aisen Pro Skin provides one-stop skincare OEM/ODM/OBM customization for global customers, including product concept, formula R&D, sample development, packaging customization, quality control, export documents, and global delivery. If you are looking for a China-based skincare OEM/ODM factory that can support international product development, contact Aisen with your product idea, target market, sales channel, expected quantity, and packaging needs. Our team will recommend a suitable product development solution and help your brand move from concept to market. Disclaimer: The information and stability data provided are based on laboratory testing and are for B2B reference only. Final formulation efficacy may vary based on specific customization and packaging. Aisen Skincare supports compliance documentation, but brand owners are ultimately responsible for meeting the regulatory requirements (e.g., FDA, CPNP) of their target markets. Products are for cosmetic use and not intended to treat any medical condition. Related products https://www.aisenproskin.com/product/anti-aging-brightening-salmon-pdrn-facial-serum https://www.aisenproski0n.com/product/bead-blue-copper-peptide-serum-with-microcapsule-tech  

  Highly active skincare ingredients such as retinol, pure vitamin C and polyphenols are generally unstable when exposed to light, oxygen and heat, and are highly prone to oxidation and degradation. This leads to the product losing its potency within a short period, a significant drop in efficacy, and skin irritation and redness. Conventional skincare products rely on antioxidants, chelating agents and light-protective packaging to merely delay degradation, rather than locking in activity at its source. In contrast, the new generation of molecular delivery systems utilises physical encapsulation, structural optimisation and precise controlled release to comprehensively resolve the issue of ingredient inactivation, whilst simultaneously ensuring formulation stability, transdermal efficiency and gentle application.   Taking 0.3% free retinol as an example, in unencapsulated traditional formulations, activity typically declines by 30%–50% following standard warehousing and 12 months on the shelf. Under extreme storage and transport conditions, residual activity may even fall below 0.15%, rendering the product virtually ineffective.       This new-generation delivery system ‘locks in’ active ingredients at a molecular level, ensuring shelf stability and precise release onto the skin.   1. Liposome encapsulation: Biocompatible protection that is both effective and gentle Liposomes, based on a phospholipid bilayer structure, are highly homologous to skin cell membranes and exhibit excellent biocompatibility. They can encapsulate active ingredients in a compartmentalised manner: water-soluble vitamin C is encapsulated within the internal aqueous phase, whilst fat-soluble retinol is embedded within the membrane layers, forming a physical protective barrier that shields against damage from light, oxygen and heat.   According to in vitro experimental data published in the *International Journal of Pharmaceutics* in 2024, following liposome encapsulation, the residual activity of vitamin C after six weeks of storage at 40°C increased from less than 30% to over 85%, the photodegradation rate of retinol was reduced by 70%, transdermal efficiency doubled, and irritation was significantly reduced (data based on laboratory tests using pure systems; results may vary slightly in commercial products).   Comparison of key advantages: After three months of storage at room temperature, traditional unencapsulated formulations retain only 20%–50% of their activity, whereas the liposome formulation maintains 80%–95% activity. It simultaneously addresses the issues of traditional formulations—where ingredients remain confined to the epidermis, absorption rates are low, and highly active ingredients are prone to causing irritation—achieving a triple balance of stability, efficacy and gentleness.       2. Nanoemulsions & NLC nano-lipid carriers: improved particle size, sustained-release formulation Nanoemulsions and nanostructured lipid carriers (NLCs) represent an advanced iteration of lipid delivery technology, suitable for poorly soluble, easily degradable and highly irritating ingredients such as retinol, resveratrol and curcumin. With particle sizes ranging from 20 to 500 nm, the Brownian motion of these extremely small droplets prevents phase separation and sedimentation, effectively dispersing poorly soluble ingredients and resolving issues of precipitation and inactivation; the only minor stability limitation arises under prolonged exposure to extreme high temperatures.   NLCs represent an upgraded version of solid lipid nanoparticles. By utilising solid-liquid mixed lipids to construct a lattice defect structure, they offer higher drug-loading capacity, greater system stability and enhanced sustained-release properties. A 2024 study published in the *International Journal of Molecular Sciences* confirmed that NLCs loaded with retinol and oligopeptides maintained stable particle size and showed no agglomeration or separation after four weeks of storage at 25°C (though reasonable variations in particle size may occur in mass-produced formulations).   Compared to traditional emulsions, NLCs are significantly superior in terms of physical stability, ingredient protection and controlled-release performance. They enable the uniform release of active ingredients such as retinol, avoiding the ‘shock’ of instantaneous high concentrations on the skin, thereby reducing issues of intolerance such as redness and stinging at the source.     3. Cyclodextrin inclusion complexes: molecular cage encapsulation for solubilisation and stabilisation   Cyclodextrin is a hollow, funnel-shaped natural polysaccharide with hydrophilic exterior and hydrophobic interior properties. It can incorporate polyphenols and fat-soluble active ingredients into its cavity via non-covalent bonds, forming stable molecular inclusion complexes. This not only shields the active ingredients from external environmental interference, significantly enhancing their light and heat stability and inhibiting degradation, but also increases the water solubility of hydrophobic components by tens to hundreds of times, thereby addressing the challenges of poor solubility, low bioavailability and susceptibility to precipitation.     4. Key differences between the old and new technologies: slowing down degradation vs. blocking degradation Traditional formulations rely on chemical antioxidants to delay ingredient degradation, but fail to address the root cause of degradation; as a result, ingredients continue to degrade and their efficacy diminishes rapidly. The new-generation delivery system employs a combination of physical isolation and molecular encapsulation, which preserves the chemical structure of the active ingredients, minimises the risk of degradation at source, significantly enhances transdermal absorption, and ensures both long-term stability of active ingredients and sustained skincare efficacy throughout the shelf life. Technical note: The delivery system cannot achieve zero degradation of ingredients over time; it can only significantly slow down the rate of degradation, which falls within the reasonable technical limits of the industry.         5. Cutting-edge breakthroughs and commercial implementation: High-end delivery technology becomes mainstream With the evolution of skincare delivery technologies, the industry has moved from traditional empirical formulations to a phase of precision molecular design. In May 2026, Amorepacific’s Lipo3Ex20nm ultra-fine liposome technology, developed in collaboration with KAIST, was featured on the cover of *ACS Nano*. This breakthrough overcame the industry-wide challenge that ‘the smaller the nanoscale, the less stable the structure’, significantly enhancing delivery efficiency. The technology has already been successfully implemented in mass production for the IOPE and Primera brands, signifying that ultra-fine nanocarrier technology has officially reached commercial maturity.   For a long time, high-end liposome, NLC and cyclodextrin delivery technologies have been monopolised by major international brands due to high R&D barriers and high mass production costs. Through its established OEM/ODM system, Guangzhou Aisen Biotechnology has modularised and standardised these three high-end delivery technologies, breaking down the barriers of technological premium pricing. This enables small and medium-sized brands to flexibly select mature carrier solutions and support small-batch production, with scaled-up costs approaching those of traditional formulations, thereby making high-end technology accessible to the masses. The application logic for these three technologies is as follows: Liposomes serve as a universal, highly compatible solution, suitable for water-soluble ingredients such as vitamin C, peptides and panthenol, and are ideal for repair, antioxidant and basic anti-ageing formulations; NLC nano-lipid carriers specialise in highly active yet gentle anti-ageing, suitable for lipophilic, potentially irritating ingredients such as retinol and curcumin, reducing skin intolerance through controlled-release mechanisms; Cyclodextrin complexes focus on improving plant extracts and hydrophobic ingredients, addressing the issues of poor solubility, precipitation and oxidation in polyphenols and essential oils; they are suitable for plant-based antioxidant and soothing formulations, and can be precisely selected and implemented according to a brand’s specific efficacy requirements.   Related products Microencapsulated Retinol Serum – gentle time-release anti-aging Centella Asiatica Ampoule – stabilized botanical repair